Lancet To Check Data On Ineffectiveness Of Hydroxychloroquine Against COVID-19

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Lancet To Check Data On Ineffectiveness Of Hydroxychloroquine Against COVID-19
Lancet To Check Data On Ineffectiveness Of Hydroxychloroquine Against COVID-19

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Video: Coronavirus Pandemic Update 80: COVID-19 Retractions & Data (Hydroxychloroquine, ACE Inhibitors) 2023, January
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Lancet to check data on ineffectiveness of hydroxychloroquine against COVID-19

One of the most reputable medical journals announced an independent audit of an article after which WHO announced the suspension of trials of the drug against COVID-19.

Lancet to check data on ineffectiveness of hydroxychloroquine against COVID-19
Lancet to check data on ineffectiveness of hydroxychloroquine against COVID-19

Hydroxychloroquine sulfate / Photo: medscape.com

The results of an independent audit are expected in the near future, The Lancet said in a statement.

This is a major international study published in The Lancet on May 22, which showed that COVID-19 treatment with chloroquine and hydroxychloroquine can be dangerous. Scientists have not found a positive effect of treatment on the course of the disease. In this regard, the World Health Organization decided to suspend its research on chloroquine and hydroxychloroquine in COVID-19 and instructed a special working group to verify the information on the safety of drugs.

In the study, scientists collected data on treatment with chloroquine and hydroxychloroquine (including, in combination with azithromycin) of almost 15 thousand people with COVID-19. More than 80 thousand patients with this infection were the comparison group. The data was collected from 671 hospitals around the world.

Patients treated with different regimens that included chloroquine and hydroxychloroquine were more likely to die than control patients. In addition, they were more likely to develop life-threatening arrhythmias. Scientists could not find a positive effect of treatment on the outcome of the disease.

However, the study leaves a number of questions. Its design (observational study) does not establish whether a particular treatment was the cause of death in these patients. The study also did not include some important patient groups: for example, those who received treatment in the advanced stages of the disease in a severe course. In addition, it remains unknown whether chloroquine and hydroxychloroquine can be used to prevent COVID-19.

Note that the Russian Ministry of Health did not exclude the use of hydroxychloroquine in the treatment of COVID-19. The drug was included in the seventh version of the methodological recommendations "Prevention, diagnosis and treatment of new coronavirus infection (COVID-19)" dated June 3.

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