Presumptive Biomarkers Of Pediatric Inflammatory Syndrome In COVID-19 Identified

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Presumptive Biomarkers Of Pediatric Inflammatory Syndrome In COVID-19 Identified
Presumptive Biomarkers Of Pediatric Inflammatory Syndrome In COVID-19 Identified

Video: Presumptive Biomarkers Of Pediatric Inflammatory Syndrome In COVID-19 Identified

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Video: Multisystem Inflammatory Syndrome in Children (MIS-C) Assocd. with COVID-19 2023, January
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Presumptive biomarkers of pediatric inflammatory syndrome in COVID-19 identified

So, according to a routine blood test, it will be possible to determine which children with COVID-19 need additional monitoring.

Presumptive biomarkers of pediatric inflammatory syndrome in COVID-19 identified
Presumptive biomarkers of pediatric inflammatory syndrome in COVID-19 identified

Photo: CC0 Public Domain

Scientists have discovered possible biomarkers predicting the development and severe course of pediatric inflammatory multisystem syndrome in COVID-19. The British edition of The Guardian told about their research.

Pediatric multisystem inflammatory syndrome is an inflammatory disorder that doctors have compared to Kawasaki disease. It is accompanied by inflammation in the vessels, which is manifested mainly by fever, skin rash, lesions on the part of the heart (the most severe of them is aneurysm of the coronary artery). This pathology has been reported by pediatricians from different countries; Italian doctors have recently described it in detail.

Scientists at Imperial College London have performed blood tests on children most affected by an inflammatory disorder similar to Kawasaki's disease. They found five of the most characteristic changes that accompany this pathology.

The most important biomarkers of inflammatory syndrome can be detected using routine testing. Ferritin and C-reactive protein are common markers of inflammation. The other three substances - troponin, brain natriuretic peptide and D-dimers - are signs of heart damage.

The authors noted that these five substances are present in the blood of patients with Kawasaki disease, and in its severe course, their concentrations are especially high. They hypothesize that these markers will help determine which children are at high risk of developing heart and multiple organ failure associated with an inflammatory syndrome.

If further research confirms the importance of these five biomarkers, doctors will have a “tool” with which they can determine which children may need care in specialized hospitals and departments.

Scientists said more research is needed on biomarkers to be called a reliable criterion that clinicians can rely on. They have already received permission for further research. They also plan to analyze which treatments are most effective for this inflammatory syndrome.

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