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Video: New Study Discourages Hydroxychloroquine For COVID-19 Treatment
New study discourages hydroxychloroquine for COVID-19 treatment
Scientists believe that this drug should not be widely used until after large studies. Earlier, the government of the Russian Federation ordered to provide educational institutions with this medicine.
In a study that included hundreds of COVID-19 patients, experimental hydroxychloroquine treatment did not show any benefit over standard disease care. The scientific work that showed this has not yet been published in a peer-reviewed scientific journal, but is available at medrxiv.org.
The study, sponsored by the US National Institutes of Health and the University of Virginia, involved 368 patients. In it, scientists compared the effectiveness of standard COVID-19 treatment with hydroxychloroquine treatment, as well as a combination of hydroxychloroquine and azithromycin.
In the hydroxychloroquine treatment group (it included 97 people), 27.8% of participants died, in the standard treatment group - 11.4%.
In this study, the use of hydroxychloroquine - alone or with azithromycin - did not reduce the need for mechanical ventilation.
The study authors believe that this drug should not be introduced into general practice until the completion of large studies.
Scientists talk about the side effects of drugs that can be used against COVID-19
Chloroquine, hydroxychloroquine and azithromycin are drug candidates for COVID-19. Scientists urge not to use them unnecessarily and be aware of the potential adverse effects of these drugs.
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The interim guidelines of the Russian Ministry of Health indicate hydroxychloroquine as an etiotropic agent against COVID-19, which is also considered a drug for the chemoprevention of the disease.
On April 16, Prime Minister Mikhail Mishustin ordered the provision of hydroxychloroquine to hospitals. The document prescribes its use for hospital patients. The popularizer of evidence-based medicine, a member of the Commission on Counteracting Falsification of Scientific Research of the Russian Academy of Sciences, Peter Talantov, criticized this order: there is practically no evidence of the effect of this drug, but its toxicity is high.
In Russia and the world, the coronavirus pandemic, which has already killed many people. Remember simple safety rules and stay healthy
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