Russian Specialists Declared The Need For Timely Vaccination Against HPV

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Russian Specialists Declared The Need For Timely Vaccination Against HPV
Russian Specialists Declared The Need For Timely Vaccination Against HPV

Video: Russian Specialists Declared The Need For Timely Vaccination Against HPV

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Russian specialists declared the need for timely vaccination against HPV

Vaccination of adolescent girls against human papillomavirus (HPV) in Scotland has revolutionized the incidence of cervical cancer and the development of precancer. If Russia does not follow this example, then in 10-20 years "there will probably be no one to fall down," leading Russian experts believe.

Russian specialists declared the need for timely vaccination against HPV
Russian specialists declared the need for timely vaccination against HPV

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Vaccination of adolescent girls against human papillomavirus (HPV) in Scotland has revolutionized the incidence of cervical cancer and the development of precancer. According to a study published in the British Medical Journal (BMJ), over the past 10 years, since the start of HPV immunization, the incidence of precancerous changes in the cervix in young women has dropped to almost zero. If Russia does not follow this example, then in 10-20 years "there will probably be no one to fall," leading Russian experts believe.

Today, cervical cancer is one of the most common cancers in women, it ranks first among the causes of cancer death in women 35-40 years old. And the advent of the HPV vaccine, which is an infection that is significantly associated with the risk of cervical cancer, has been a major advance in immunization. In the world, 86 countries have already included the HPV vaccine in their national immunization program, and 16 of them vaccinate not only girls, but also boys. This is necessary in order to reduce the spread of virus strains, in addition, some types of HPV can provoke some types of cancer in men.

The study, conducted by scientists from several universities in Scotland, analyzed data from the screening of about 140 thousand young women who were vaccinated against HPV between 2008 and 2016. The result exceeded all expectations: the number of precancerous diseases of the cervix decreased by 90%. Moreover, the study found that the incidence of HPV-associated diseases also decreased among women who did not undergo preventive vaccination, which indicates an increase in herd immunity to the virus among the country's population.

The HPV vaccination program in Scotland has been recognized as highly effective and, according to the authors of the study, its results in the future may form the basis of a program for the prevention of cervical cancer and other HPV-associated cancers around the world. The results of the study and the situation in our country were commented on by leading Russian experts.

Director of the Research Institute of Carcinogenesis, National Medical Research Center of Oncology. N.N. Blokhin, Corresponding Member of the Russian Academy of Sciences, Visiting Professor at Oxford University David Zaridze:

“In Russia, morbidity and mortality from cervical cancer is growing. This disease takes the lives of 17 women in our country every day. Most often, due to cervical cancer, women die at a young, reproductive and working age - 25-40 years. Over the past 10 years, the incidence has increased by about 26%. More than a third (32%) of primary diagnoses of cervical cancer are made already at advanced (III and IV) stages of the disease."

Chief specialist gynecologist for children and adolescents of the Ministry of Health of Russia, MD Elena Uvarova:

“In Russia, vaccination against HPV is slow and ineffective, despite its effectiveness, proven in the experience of many countries. It has been proven that cervical cancer is almost 100% caused by the presence of HPV infection. According to various sources, in the first year of sexual activity, infection occurs in 42% of young people, and during the first five years, almost 100% of the sexually active population becomes infected with the virus. The most effective vaccination against HPV before the first meeting with the virus, that is, before the onset of sexual activity - at the age of 12-13 years. It is at this age that a pronounced immune response after vaccination against highly oncogenic types of the virus is formed quickly and lasts for a long time. We can, and therefore must, protect the future of our children from the life-threatening negative consequences of HPV by vaccinating them on time."

Chief freelance pediatric specialist in preventive medicine of the Ministry of Health of Russia, head Department of Faculty Pediatrics, Russian National Research Medical University named after N.I. Pirogova, Academician of the Russian Academy of Sciences Leila Namazova-Baranova:

“Today, in 91 countries of the world, HPV vaccination is included in national immunization programs, more than 20 of them use a gender-neutral approach, when not only girls are vaccinated, but also boys. In Russia, HPV vaccination is still available only for some adolescents and only in 27 regions - within the framework of regional calendars. These programs have also shown positive results, but the cumulative vaccination coverage of adolescents is only a few percent of the target group. But in order for us to achieve a decrease in the incidence of cervical cancer and other HPV-associated cancers in the long term, vaccination coverage must be at least 90%! That is, if today vaccination is not made available to all target groups, then in 10-20 years there may already be no one to save”.

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