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Video: Benefits Of HPV Vaccination Are Evident Even At The Age Of 20
Benefits of HPV vaccination are evident even at the age of 20
New research demonstrates the early benefits of vaccination against human papillomavirus (HPV). Scientists have determined that routine vaccination of girls under 13 in Scotland, carried out since 2008, has led to a sharp decrease in the number of cervical diseases by the age of 20, including diseases that increase the risk of developing cancer
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New research published in British Medical Journa 1 demonstrates the early benefits of vaccination against human papillomavirus (HPV). Scientists have determined that routine vaccination of girls under 13 in Scotland since 2008 has led to a sharp decline in cervical disease by age 20, including diseases that increase the risk of cervical cancer later in life.
There are over 100 different types of HPV. Most of them do not give any symptoms, and some can cause irritating but harmless warts on the hands, feet, or genitals. However, there are types of HPV that cause changes that can ultimately lead to cancer. They are associated with almost all cases of cervical cancer, as well as a significant proportion of cancers of the mouth, throat, anus, and penis.
Until recently, there was only a vaccine against the two most common types of high-risk HPV, but it was recommended only for adolescent girls. Over time, the use of the vaccine has expanded, as has the number of HPV types it protects against. The newest version of the vaccine protects against seven high-risk HPV types, which cause approximately 90% of cervical cancers (along with two types that cause genital warts). Now vaccination is recommended for both boys and adult men and women under 45.
However, childhood vaccination is most beneficial because HPV is easy to get infected when you start sexual activity. In many countries, including the United States, childhood HPV vaccination rates are still extremely low. However, in Scotland, routine vaccination of girls was carried out en masse, thanks to a publicly funded program, which allows assessing its effects at the national level.
Scientists studied data from more than 130,000 women in Scotland who had a cervical examination at the age of 20. They then compared data from women vaccinated against HPV during childhood with data from older women who were vaccinated later, and with data from unvaccinated women born in 1988.
They found that compared to unvaccinated women, those who had been vaccinated against HPV in childhood were much less likely to develop any disease associated with the growth of abnormal cells in the cervix. Most importantly, the prevalence of cervical dysplasia has decreased by almost 6%. And this is very important because this condition puts women at the greatest risk of developing cervical cancer.
In women vaccinated at an older age, the incidence rate was higher than in those vaccinated in childhood, but lower than in those who were not vaccinated at all.