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Video: Vaping Has The Same DNA Carcinogenic Effects As Regular Smoking
Vaping has the same DNA carcinogenic effects as regular smoking
The same molecular changes associated with cancer occur in the oral tissues of e-cigarette users as in smokers. This heightens growing medical fears that e-cigarettes are not a harmless alternative to smoking.
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The same molecular changes associated with cancer occur in the oral tissues of e-cigarette users as in smokers, according to a small study by the University of South California, published in the International Journal of Molecular Sciences. This reinforces growing medical fears that e-cigarettes are not a harmless alternative to smoking.
According to recent studies, vaping has been found to be nearly twice as effective as other nicotine replacement therapies in helping to quit smoking. However, e-cigarette smoking is becoming more and more popular among teens and there is evidence that vaping will lead to nicotine addiction and future smoking.
The researchers examined the expression of genes in oral cells collected from 42 e-cigarette users, 24 regular cigarette smokers and 27 people who did not smoke at all. Gene expression is the process by which hereditary information is converted into a functional product (protein). Certain changes in gene expression can lead to cancer.
Scientists have focused on oral epithelial cells because more than 90% of smoking-related malignancies occur in epithelial tissue, and oral cancer is associated with tobacco use.
Both regular smokers and vapers have shown abnormal expression - deregulation - of a large number of genes associated with cancer. 26% of deregulated genes in e-cigarette users were identical to those found in smokers. Some deregulated genes found in e-cigarette users can lead to cancer of the lungs, esophagus, bladder, ovaries and leukemia.
“Existing data shows that e-cigarette vapor is more than just 'water vapor'. Although the concentrations of most carcinogenic compounds in e-cigarette products are much lower than in cigarette smoke, there are no safe levels of carcinogen exposure, as some people believe, "said study lead author Ahmad Besaratinia, associate professor at Keck School of Medicine. School of Medicine) of the University of Southern California.
The molecular changes observed in the study are not cancer or even a precancerous condition, but rather an early warning of a process that could potentially lead to cancer if left unchecked.
The team plans to replicate the study in a large group of participants and explore the mechanisms that cause gene deregulation. In addition, they are running an experiment in which smokers switch to e-cigarettes, in order to find out if there are changes in the regulation of genes.