Scientists Argue That "bad Cholesterol" Is Just A Hyped Myth

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Scientists Argue That "bad Cholesterol" Is Just A Hyped Myth
Scientists Argue That "bad Cholesterol" Is Just A Hyped Myth

Video: Scientists Argue That "bad Cholesterol" Is Just A Hyped Myth

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Scientists argue that "bad cholesterol" is just a hyped myth

A new review of research over the past fifty years by an international team of physicians and published in the Expert Review of Clinical Pharmacology challenges half a century of belief that "bad cholesterol" (low density lipoprotein, LDL) causes cardiovascular disease. Accordingly, the benefits of drugs that reduce their levels are also questioned.

Scientists claim that
Scientists claim that

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A new review of research over the past fifty years by an international team of physicians and published in the Expert Review of Clinical Pharmacology challenges half a century of belief that "bad cholesterol" (low density lipoprotein, LDL) causes cardiovascular disease.

Cardiologists from the USA, Sweden, UK, Italy, Ireland, France, Japan and other countries (17 people in total) found no evidence of a link between high total or "bad" cholesterol and cardiovascular disease, analyzing data from 1.3 million patients … They said this view is based on "misleading statistics, eliminating test failures and ignoring numerous conflicting observations."

The review also raises the question of the use of statins as the main means of preventing cardiovascular diseases. This could have serious repercussions, as tens of millions of people are now taking statins to lower cholesterol and prevent myocardial infarction.

“For decades, there has been research designed to mislead the public and doctors into believing that LDL causes heart disease when it really isn't,” said David Diamond, one of the review authors, Ph.D., professor of psychology and molecular pharmacology and physiology of the University of South Florida (University of South Florida). “The study that targeted LDL is horribly flawed. Not only is there no evidence of a causal relationship between LDL and heart disease, but the statistical approach that statin advocates have used to demonstrate the benefits has been misleading.”

The effectiveness of statin treatment as primary prevention has been discussed by researchers for several decades. The review indicated that these drugs have "subtle benefits and serious side effects." An analysis of data in 12 European countries from 2000 to 2012 showed no association between statin use and reductions in mortality.

At present, the review noted, claims of positive statin test results have “evaporated” as, according to the rules introduced in 2005 by the European and US health authorities, all sample data must be made public.

“We suggest that clinicians move away from statins and PCSK9 inhibitors and instead identify and uncover the actual causes of cardiovascular disease,” said review co-author Sherif Sultan of Irish Galway Clinic, professor at the International Society vascular surgery (International Society for Vascular Surgery).

The researchers discovered a curious thing: patients with acute myocardial infarction had lower levels of "bad" cholesterol, while healthy people with low "bad" cholesterol had a significantly increased risk of infections and cancer. But the most important finding was that older people with high LDL levels live the longest.

Thus, high levels of "bad" cholesterol are beneficial in terms of overall life expectancy. And in order to prevent cardiovascular disease, it is recommended to follow a low-carb diet for weight loss.

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