Silicone Breasts Increase The Risk Of Developing Several Diseases

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Silicone Breasts Increase The Risk Of Developing Several Diseases
Silicone Breasts Increase The Risk Of Developing Several Diseases

Video: Silicone Breasts Increase The Risk Of Developing Several Diseases

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Video: New breast implant study launched as risk evidence mounts 2023, February
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Silicone breasts increase the risk of developing several diseases

Women with silicone breast implants are at an increased risk of certain diseases compared to others. First of all, we are talking about autoimmune diseases, but the list of risks is not limited to them.

Silicone breasts increase the risk of developing several diseases
Silicone breasts increase the risk of developing several diseases

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Women with silicone breast implants are at increased risk for certain diseases compared to others, according to a study published in the Annals of Surgery.

Scientists from the Oncological Center M.D. Anderson University of Texas MD Anderson Cancer Center in Antwerp, Houston, analyzed data from the largest study on the safety of silicone breast implants.

In the early 1990s, the Food and Drug Administration (FDA) banned the use of silicone implants in response to public concerns about health risks, including cancer, connective tissue diseases, and autoimmune diseases. However, studies have not found an association between breast implants and these diseases. In 2006, the FDA approved silicone gel implants from two manufacturers - Allergan and Mentor Corp - subject to large postapproval studies (LPAS) to monitor long-term health and safety outcomes.

Scientists analyzed data from nearly 100,000 patients enrolled in the LPAS between 2007 and 2009-2010. More than 80,000 of them have supplied silicone implants; the rest are implants filled with sterile saline. This extensive database allowed researchers to assess the risk of rare adverse outcomes.

It turned out that women with silicone implants were at increased risk of several rare diseases compared to the general population. These conditions are classified as autoimmune or rheumatologic disorders: Sjogren's syndrome (eight times the risk in the general population), scleroderma (seven times the risk), and rheumatoid arthritis (about six times the risk).

Silicone implants were also associated with a 4.5-fold increase in the risk of stillbirth, a modest increase in the risk of miscarriage. The risk of melanoma, a dangerous type of skin cancer, was nearly four times higher. There was no significant association with suicide risk suggested in the previous study. The database included only one case of implant-associated anaplastic large cell lymphoma, a rare but dangerous type of cancer previously associated with breast implants.

Compared to saline-filled implants, silicone implants had a higher risk of some surgical complications. These include capsular contractures (scars around the implant), which occurred in 5.0% of cases with silicone implants versus 2.8% of implants with saline. Capsular contracture was the most common cause of reoperation in this group, with 7.2% of primary breast augmentation procedures.

Although some rare diseases appear to be more common in women with silicone implants, the absolute rates of these adverse outcomes were low. The researchers emphasize that their results are not convincing because of the inherent limitations of using post-registration databases, including the lack of complete patient information and separate follow-up data.

“An unbiased analysis of this data is essential to address the remaining uncertainty in the evidence base,” noted Dr. Mark W. Clemens and colleagues. “It is the responsibility of the plastic surgeon community to provide comprehensive evidence of the risks associated with breast implants.”

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