The Most Popular Pain Reliever Increases The Risk Of Heart Attack And Stroke By 50%

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The Most Popular Pain Reliever Increases The Risk Of Heart Attack And Stroke By 50%
The Most Popular Pain Reliever Increases The Risk Of Heart Attack And Stroke By 50%

Video: The Most Popular Pain Reliever Increases The Risk Of Heart Attack And Stroke By 50%

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Video: Common painkiller could increase risk of stroke and heart attack by 50%, study finds 2023, February
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The most popular pain reliever increases the risk of heart attack and stroke by 50%

The new study focused on the side effects of diclofenac. It turned out to be more dangerous for the heart and blood vessels than other similar drugs.

The most popular pain reliever increases the risk of heart attack and stroke by 50%
The most popular pain reliever increases the risk of heart attack and stroke by 50%

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One of the more popular pain relievers can be dangerous to your cardiovascular health. This is evidenced by the results of a new study recently published in the British Medical Journal (BMJ).

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to relieve pain. In the USA alone, they are accepted by about 30 million people.

Although NSAIDs are commonly recommended for the treatment of inflammation, headaches, and fever, these drugs are thought to increase the risk of certain cardiovascular diseases.

Due to ethical concerns, this risk cannot be assessed in clinical trials, so the European Society of Cardiology conducted an extensive review of existing research on this topic and concluded that non-aspirin NSAIDs should not be prescribed to individuals at high risk of heart disease … They should also not be sold without “proper warning of the high incidence of cardiovascular complications” caused by these drugs.

The new study focuses on one NSAID drug, diclofenac. Danish scientists, led by Morten Schmidt of Aarhus University Hospital, decided to study the cardiovascular risk associated with taking this pain reliever, which they identified as "the world's most widely used NSAID."

A group of Danish researchers examined 252 national studies to obtain information on more than 6.3 million Danes over a 20-year period (1996-2016). The average age of the study participants was 46-56 years.

Researchers studied the risk of cardiovascular disease with diclofenac versus that of paracetamol, ibuprofen, or naproxen.

After adjusting for potentially confounding factors, the researchers found that within 30 days of taking diclofenac, the incidence of major cardiovascular disorders, such as arrhythmia, ischemic stroke, heart failure, and heart attack, was significantly higher compared to other NSAIDs.

The risk of such cardiovascular diseases was 50% higher in those who started taking diclofenac compared to those who did not take any drugs. Compared to taking paracetamol or ibuprofen, those taking diclofenac had a 20% higher risk of cardiovascular disease.

In addition, the authors reported that taking diclofenac increased the risk of upper gastrointestinal bleeding by about 4.5 times compared with those who did not take any drugs and 2.5 times compared with taking ibuprofen or paracetamol.

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